Renal disease : genetic diagnosis and the patient’s journey

Familial renal disease

John Sayer is a Clinical Professor of Renal Medicine, Newcastle University and runs the Renal Genetics Service and Family Renal Genetic clinic at Newcastle Upon Tyne Hospitals NHS Foundation Trust. He published a case report including both the clinical and patient perspectives to think about the consequences of analysing genes to discover the underlying cause of disease, and the impact such a genetic diagnosis has on the patient and their family.

Health care and social media: educating the digital patient

Social media has become prolific in everyday life and allows the instantaneous sharing of information, which can include health care information. The authors of a Research Note published on F1000Research suggests as medical vocabulary becomes more prevalent on social media that more comprehensible language should be used. In this guest blog, Farris Timimi, cardiologist, Medical Director of the Mayo Clinic Social Media Network and well-known health care Twitter user gives his view on this.

An author and reviewer in conversation – reproducibility and antibody validation

A recent Opinion Article by Jan Voskuil, Aeonian Biotech, discussed the challenges in validation of research antibodies. It was openly peer reviewed by Michael Weller, Federal Institute for Materials Research and Testing (BAM), Germany. In this blog, both discuss these challenges, the reproducibility crisis and open data.

Understanding working practices of scientists

Nick Riddiford is a postdoc in developmental biology in Institut Curie in Paris. Last year he surveyed scientists to find out more about their working practices. He published his results on F1000Research as a research article. He explains more here about why he carried out the survey and what he thinks needs to change.

I’m fine, on the outside

Mental health

This week is Mental Health Awareness Week, and the Mental Health Foundation hopes to improve the wellbeing and mental health of Britain, after their survey revealed that the nation’s state of mental health is poor and appears to be deteriorating.
As the Foundation is investigating ways to prevent mental health and enhance society’s mental state, I thought I would investigate some of the research that has been recommended by our F1000Prime Faculty Members on the suggested influences and causes of mental illness, as well as possible treatments.

What should you be aware of when developing new biomedical software?

Biomedical software

It is time to re-think how biomedical applications are built and adopt new strategies that ensure quality, efficiency, robustness, correctness and reusability of software components. Dr Luis Bastiao Silva explains how engaging end-users during the development process will help to ensure that software applications fit the needs of general clinicians and practitioners.