A perfect storm

I’ve been following the developing story of NDM-1, an enzyme that confers antibiotic resistance to gram-negative bacteria, since before the first article on its appearance was published in The Lancet Infectious Diseases in August last year (see F1000 evaluations). At the time, many of the cases of infection in India – but not all –…

Benny Bacterium

Those of you who know anything about British popular culture will no doubt be familiar with Benny Hill. The Benny Hill Show was long-running and immensely popular—although it was often accused of being sexist, it was the men who were usually shown up to be idiots (admittedly in the presence of scantily clad females). Very…

HIV vaccines–the future?

Did you catch the vaccine issue of The Scientist? It features F1000 Members Robin Weiss and Gene Shearer (with Adriano Boasso), writing about the history and future of vaccination and an unusual but potentially effective alternative vaccination strategy.

F1000 Members among first HHMI-GBMF investigators

We’re pleased to congratulate the following five F1000 members who are among the first fifteen joint Howard Hughes Medical Institute / Gordon and Betty Moore Foundation investigators. This is a joint initiative supporting basic plant science research. The two organizations are investing a total of US$75 million over the five years of the initial appointments,…

Invisible colleges and team science

There’s an interesting article just out in Issues in Science & Technology Librarianship, which “publishes substantive content of interest to science and technology librarians.” Written by John Carey, head librarian at Hunter College, City University of New York, the article examines the concept of “invisible colleges“: mechanisms that promote dissemination of knowledge and fuel the…

Lister's Legacy

If you’re a fan of sex and dirt (and who isn’t, these days?), and happen to be within striking distance of the Euston Road tomorrow evening, check out this free event at the Wellcome Collection, The thing is…Lister’s legacy, 15 June 2011, 19.00 – 20.00. This is a discussion with “Quentin Cooper, Hugh Pennington and…

"A previously unknown world"

“Research is one of the most exciting ways to spend your time” — Jo Handelsman How do you study the genomes of organisms that can’t be grown in the lab? Jo Handelsman at Yale is interested in the impact of small molecules produced by microbes, or their hosts, on the nature and robustness of microbial…

Science knits

What is it about science and knitting? The number of times I’ve been to a talk or panel discussion and there’s people sitting there click-clacking away. I think I’ve finally figured out what it is-they’ve all been practising for the Cheltenham Science Festival. Artist Alison Thomson has been collaborating with the British Society for Immunology…

Twitter journal club–update

The first ever* Twitter journal club (Monday’s NS) was a huge success. Natalie Silvey has now posted a summary of last Sunday’s chat. She draws out five headline discussion points: Randomized control trials and the issue of written informed consent Methodology, particularly blinding The importance of a (misleading) headline result The effect of single-centre studies…

Mending broken hearts–a step closer

A piece of basic research made it into even mainstream news sites yesterday: the finding that the peptide thymosin ß4 can prime adult cardiac epithelium to produce new muscle cells after a heart attack. Getting the heart to regenerate itself after injury is a goal of the British Heart Foundation’s campaign to ‘Mend Broken Hearts’,…