When you want to know how a protein works (and sometimes, if other avenues have been exhausted, what it does), the usual approach is to solve its atomic structure. You can do this by X-ray crystallography or nuclear magnetic resonance spectroscopy, but whichever you choose (rather, whichever actually works for you) you’re going to need…
This week’s news includes the hottest experimental cancer drugs, two techniques that aim to avoid immune rejection of transplanted organs, and a long-lost tree rat that shows its face for the first time in more than 100 years.
As well as the usual crop of interesting evaluations this week (see our Facebook page for some free links) there have been a couple of comments about papers and their evaluations. David Enard of Stanford University responds to an evaluation of his own paper, Human and non-human primate genomes share hotspots of positive selection10.1371/journal.pgen.1000840. In…
The Royal Society has just announced its new Fellows for 2011. We’re pleased to congratulate the following F1000 Members on their election: Professor Alun M. Davies FRS, Neuroscience Section Head Professor Nick Peter Franks FRS, Anesthesiology & Pain Management Dr Patrick Tam FRS, Developmental biology Professor Angela Vincent FRS, Neuroscience Faculty Head Professor Joanne Chory…
An update on the story of Jonathan Eisen and his late father’s papers: David Dobbs in Wired writes that Eisen has managed to get PDFs for almost all the papers, and they’re available at Mendeley. Well done!
The Centers for Disease Control and Prevention should be your first stop for ‘credible, reliable’ health information. It’s good to see that they’ve finally woken up to a very real yet often overlooked threat, and have a blog post detailing the things you should get ready in case of a zombie apocalypse. Of course, it’s…
Morgan‘s posts about careers, science and science funding seem to strike nerves with some of our readers. One thing Morgan hasn’t addressed, although I’m sure it’s on her list, is leadership. We’ve just published an evaluation of an article in the Harvard Business Review, The Wise Leader, in their ‘The Big Idea’ series. The two…
On Monday we reported on a trial showing that early retroviral treatment can protect partners of HIV-infected individuals. The findings are so good that the data were released early by the interim review board. This must put a smile on the face of Anthony Fauci, who has made great contributions to understanding how HIV destroys…
“You are losing any semblance of scientific credibility.” That quote is from an email I received this morning, in response to a message I sent out to some folks on my email list. What was in my message that provoked such a strong response? Speculations about alien landings in Nebraska? Discussions of Big Foot sightings?…
This week’s news includes the surprising immune rejection of induced pluripotent stem cells, a WHO gathering to discuss the fate of two remaining stocks of smallpox virus, the use of AIDS drugs to prevent HIV transmission, Salmonella sweeping across US labs, the debate over why the blind have an improved sense of touch, and a…
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