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Kathleen Wets, Editorial Director of Biology, met Faculty Member Jan Lammerding at the American Society for Cell Biology (ASCB) meeting late last year.

Jan is a member of the Cytoskeleton section, and is Assistant Professor in the Department of Biomedical Engineering and the Weill Institute for Cellular and Molecular Biology at Cornell University in New York. He spoke about his lab’s current research on the mutations that can affect the mechanical properties of the cell nucleus and can thereby cause diseases such as muscular dystrophy and may even have a role in cancer metastasis:

Jan’s research particularly focuses on nuclear envelope proteins such as lamins, which have also been associated with cell proliferation. Read Jan’s latest F1000 evaluation of an article that “further forces re-evaluation of the long-held assumption that B-type lamins are essential for cell viability and play an important role in transcriptional repression during differentiation.”