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Cell biologists are a grumblesome lot. They always want more–more fluorophores, more microscopes, more photon yield… A technical advance in Nature Methods uses Bessel beam illumination to provide rapid three-dimensional imaging, creating what F1000 Member Bob Goldstein at UNC Chapel Hill calls “truly stunning” films of live cells.

Do check out Bob’s evaluation, and the blog post at HighMag that tipped him off. Also check out the supplementary videos that the authors made using this technique. You should be able to get there without a subscription, but you can also try loading the movies directly using links of the form https://www.nature.com/nmeth/journal/v8/n5/extref/nmeth.1586-SN.avi where ‘N’ is a number from 2 to 13, e.g. https://www.nature.com/nmeth/journal/v8/n5/extref/nmeth.1586-S13.avi.