blog

A selection of new content on F1000Research from the past week. To receive notification of all new articles, sign up for our table of contents alerts.

Featured article

Design and conduct of Xtreme Everest 2: An observational cohort study of Sherpa and lowlander responses to graduated hypobaric hypoxia [v1; ref status: indexed, https://f1000r.es/57m]

Edward Gilbert-Kawai, Adam Sheperdigian, Thomas Adams, Kay Mitchell, Martin Feelisch, Andrew Murray, Mark Peters, Grace Gilbert-Kawai, Hugh Montgomery, Denny Levett, Rajendra Kumar, Michael Mythen, Michael Grocott, Daniel Martin

The Sherpa population of Nepal is much better at dealing with the low oxygen conditions high in the Himalayas than other people are. This study protocol describes the design of a cohort study to further investigate the biological difference between the Sherpas and lowlanders in adapting to the change in oxygen levels when climbing Mount Everest.

 

Articles that recently passed peer review

Characterization of population-based variation and putative functional elements for the multiple-cancer susceptibility loci at 5p15.33 [v1; ref status: indexed, https://f1000r.es/49o]
Lisa Mirabello, Charles C. Chung, Meredith Yeager, Sharon A Savage

Prediction of multi-drug resistance transporters using a novel sequence analysis method [v2; ref status: indexed, https://f1000r.es/5ef]
Jason E. McDermott, Paul Bruillard, Christopher C. Overall, Luke Gosink, Stephen R. Lindemann

Interactive lectures: Clickers or personal devices? [v1; ref status: indexed, https://f1000r.es/54w]
Lesley J. Morrell, Domino A. Joyce