Pain and origins in female physiology

Pamela Flood is a professor at the UCSF School of Medicine, and an F1000Prime Faculty Member in the Obstetrical Anaesthesiology section.

Here, Professor Flood talks about her lab’s current research into the science of pain, particularly in women. Looking predominantly at labour, Professor Flood’s group have used studies in mice to develop a behavioural scoring system and mathematical model for pain. Analysing both demographic and genetic data, these models can be used for clinical trials in humans to help understand the variability in the pain of giving birth.

Ray Rodgers is a Principal Research Fellow of the National Health and Medical Research Council of Australia and an Associate Professor at the University of Adelaide, Australia. He is also a Faculty Member in the Reproductive Physiology section of F1000Prime.

In this interview, Professor Rodgers tells us how studying the ovary is no mean feat; it is a field that requires a breadth of knowledge across many areas of cell biology, which is where he finds F1000Prime most useful. The biggest recent discovery in this area is that of how the ovary develops during foetal life from a newly discovered set of cells. Professor Rodger’s group are currently using their knowledge of ovarian physiology to work on a hypothesis for the origins of polycystic ovary syndrome.

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