World Alzheimer’s Day
| 21 September, 2013 | Eva Amsen |
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September 21st is World Alzheimer’s Day, and we’d like to mark this by highlighting two F1000Research papers from the past year that have been received very well (you can read the public referee reports on each article) and that both reported new discoveries related to Alzheimer’s disease.
Sometimes it might feel that progress in disease research is very slow, but as you can see from these papers, researchers are constantly discovering new things:
A new player in the development of Alzheimer’s disease
In degenerative brain diseases, such as Alzheimer’s disease, nerve cells die while their support cells activate the
brain’s immune system to cause further damage. Adrian Pini, Jonathan Gilthorpe and Andrew Lumsden at the MRC Centre for Developmental Neurobiology at King’s College London, have found that a single protein, histone H1, causes these distinct outcomes. This discovery may lead to the development of new drugs that can slow the onset of Alzheimer’s disease.
–Read the paper and referee reports
Air pollution causes Alzheimer’s disease
Young people living in areas with high levels of air pollution show signs of Alzheimer’s Disease, but is air pollution really the cause of the disease? Sam Gandy, of the Icahn School of Medicine at Mount Sinai in New York, was able to demonstrate that mice exposed to air pollution in experimental conditions showed an increase of Alzheimer disease markers in their brains, suggesting that there is indeed a direct effect of air pollution on Alzheimer’s disease.
-Read the paper and referee reports
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