To honor our 2012 Nobel Laureates, Sir John Gurdon (Developmental Biology) and Brian Kobilka (Structural Biology), we’ve made their F1000 recommendations free to view for all readers.

Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR4.
Kofuku Y, Yoshiura C, Ueda T, Terasawa H, …, Takahashi H, Terashima Y, Matsushima K, Shimada I.
J Biol Chem. 2009 Dec 11; 284(50):35240-50
Evaluated by Brian Kobilka and Michael Bokoch (02 Aug 2010)
The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.
Mansour AA, Gafni O, Weinberger L, Zviran A, …, Horn-Saban S, Amit I, Novershtern N, Hanna JH.
Nature. 2012 Aug 16; 488(7411):409-13
Evaluated by John Gurdon and Vincent Pasque (06 Sep 2012)
Polycomb function during oogenesis is required for mouse embryonic development.
Posfai E, Kunzmann R, Brochard V, Salvaing J, …, van Lohuizen M, Vidal M, Beaujean N, Peters AHFM.
Genes Dev. 2012 May 1; 26(9):920-32
Evaluated by John Gurdon and Kei Miyamoto (28 Jun 2012)
Embryonic Stem Cells Induce Pluripotency in Somatic Cell Fusion through Biphasic Reprogramming.
Foshay KM, Looney TJ, Chari S, Mao FF, …, Gaetz J, Di CG, Xiang AP, Lahn BT. Mol Cell. 2012 Mar 20
Evaluated by John Gurdon and Kei Miyamoto (20 Apr 2012)
Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution.
Ulitsky I, Shkumatava A, Jan CH, Sive H, Bartel DP.
Cell. 2011 Dec 23; 147(7):1537-50
Evaluated by John Gurdon and Vincent Pasque (22 Feb 2012)
Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation.
Zhao R, Nakamura T, Fu Y, Lazar Z, Spector DL. Nat Cell Biol. 2011 Nov; 13(11):1295-304
Evaluated by John Gurdon and Vincent Pasque (20 Feb 2012)
Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1.
Wang W, Yang J, Liu H, Lu D, …, Guo G, Zhang S, Bradley A, Liu P. Proc Natl Acad Sci U S A. 2011 Nov 8; 108(45):18283-8
Evaluated by John Gurdon and Vincent Pasque (28 Nov 2011)
Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis.
Lund E, Sheets MD, Imboden SB, Dahlberg JE. Genes Dev. 2011 Jun 1; 25(11):1121-31
Evaluated by John Gurdon and Vincent Pasque (03 Aug 2011)
Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer.
Inoue K, Kohda T, Sugimoto M, Sado T, …, Yang X, Ishino F, Abe K, Ogura A. Science. 2010 Oct 22; 330(6003):496-9
Evaluated by John Gurdon and Vincent Pasque (25 May 2011)









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