Energize

Ever wondered just what the heck is going on? Elly Strammer had one of those moments reading the comments on an article first evaluated by Yehezkel Ben-Ari at the Institut de Neurobiologie de la Méditerranée, France. The article, Spontaneous network events driven by depolarizing GABA action in neonatal hippocampal slices are not attributable to deficient…

Biomarkers: a pile of CRP?

Here at F1000 we’re big fans of John Ioannidis’s work. He continues to be a zealous (in the best sense) promoter of the basic tenets of the scientific method and the design, execution and reporting of clinical studies. His 2005 paper in PLoS Medicine is still the most viewed article on F1000 (and most viewed…

On taking a good look at ourselves

Perhaps the most distinctive and powerful thing about Science is its tendency, or rather proclivity to ask searching, even uncomfortable questions. And unlike belief systems, or ideological and political and movements, or pseudoscience, it asks those questions of itself. There’s been a fair bit of that going on recently.

It had to be you

One of the biggest problems facing authors of scientific papers is the ordering of the author list. In my own field, the person who did the most work (or who had the bright idea, &c.) would tend to go first, and the person running the lab in the prestigious last author position. (My own experience…

No definite link between cannabis use and suicide: our review

We’ve published an interesting review (aren’t they all though?) on a study that discussed the lack of association between marijuana and suicide risk, in what our reviewer Wayne Hall from the University of Queensland, Australia, described as “the largest and best controlled prospective study of the relationship to date“. It’s a tough topic to tackle,…

Half The Lies You Tell Ain't True

You’ve probably seen all the fuss over Wyeth and the ghost-writing of medical articles, along with the associated smugness of certain commentators. According to my contacts in the medical comms industry, the practice as such is nothing new, and there are very, very strong guidelines. The creative outrage we’re seeing is really rather misplaced: Well,…