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Editorial Director of Biology Kathleen Wets caught up with Stefan Linder, Faculty Member in the Cytoskeleton section and Professor of Cellular Microbiology at the University Medical Center in Eppendorf, Germany, at the American Society for Cell Biology (ASCB) meeting last year.

Here, he explains his research focuses, in particular, the cytoskeletal regulation of human macrophages and endothelial cells via actin regulatory mechanisms and intracellular trafficking along microtubules:

Another of their chief lines of research concerns podosomes, actin-rich adhesion structures in macrophages that are a great system with which to study actin turnover because of their many levels of dynamics. Podosomes are adhesion and invasion structures, which makes them relevant to human pathology and physiology.

Read Stefan’s latest F1000 evaluation of a paper that “reveals a new and highly flexible actin-based form of long-range transport and has wide-ranging impact on many aspects of intracellular trafficking.”