Another year, another great set of recommendations from our Faculty Members. To round off 2014 and showcase the brilliant writing of our Faculty, we’ve put together a list of our favourite quotes from F1000 recommendations this year – we hope you enjoy.
From all of us at F1000, we hope you have a fantastic Christmas and a very happy new year! We’ll be back in 2015 with many new updates and features.
“I have seldom felt as stupid as I did after reading this paper.”
Lauri Oksanen on 100,000-year glacial cycles. The long cycle could be due to the impact of the glaciers on the underlying bedrocks.
“Dengue virology is now resorting to the arts of alchemy”.
How to transform a dengue-3 virus into dengue-4. Scott Halstead highlights a study that could have implications for vaccine design.
“Assuming mice tell true stories, pregnant mums may need to eat carrots!”
Barry Rouse reports on experimental studies showing that maternal intake levels of vitamin A during pregnancy have a major effect on postnatal immunocompetence.
“Ever look a horse in the mouth? It’s a good idea … to assess the hedonic palatability or ‘liking’ for what the horse is eating.”
Horses’ responses to sweet and bitter tastes are similar to ours, according to Kent Berridge, providing support for the taxonomically widespread expression of hedonic responses to sweet and bitter.
“Beards are so attractive these days. Is it all Hollywood and social media …?”
What makes beards attractive? The fact that they’re rare, apparently, say Bryan Neff and Tim Hain, aka negative frequency-dependent selection.
“This investigation illustrates the microbial equivalent of ’50 ways to leave your lover’…”
Joseph Heitman on abandoning sex: frequent independent losses of sexual potential have occurred in diverse species of Tetrahymena.
“This article makes me want to grab the desk lamp from my office, run to the nearest hood and try the chemistry – today.”
Robert Garbaccio thinks this protocol, a merger of photoredox catalysis and nickel catalysis allowing the direct cross-coupling of sp3-sp2 centres without the need for pre-activated partners, opens up a chemist’s toolbox considerably.
“Caenorhabditis elegans worms can cut themselves in two – and survive!”
Bob Goldstein tells a tale of C. elegans; bacteria can stick them together by the tails, BUT they can self-sever.
“What insights can we learn from studying obesity-related variables as they relate to sexual orientation?”
David Allison reminds us that when we study outside of the usual range of our observations, we often learn new things. Studying persons of diverse sexual orientations is important for delivering the best health information and care possible.
“Physics is the alphabet, chemistry is the dictionary, biology is literature.”
Nando Boero‘s take on the article “A theoretical physicist’s journey into biology: from quarks and strings to cells and whales.”
“Baldies reading this may get quite excited but, unfortunately, this approach is not going to work for androgenic alopecia (or male pattern baldness) … perhaps good news for their partners who find their bald-headed men sexy… “
Ali Mobasheri highlights a mouse model of alopecia areata in which hair loss driven by cytotoxic T lymphocytes may be reversed by Janus kinase protein tyrosine kinase inhibition. Three patients achieved near-complete hair regrowth within five months of treatment.
We’ve reserved a section for quotes from Faculty Member David Triggle, who has a special talent for making articles come alive with his quirky writing style!
“We need a new discipline – perhaps termed ‘Zombie Pharmacology’ – offering potential for new neuroactive drugs.”
Talking on a study in which fungal parasites manipulate ant brains to control behavior, David Triggle further comments, “parasites have been aptly referred to as ‘evolution’s neurobiologists’ – high praise indeed!”
“Will “bacteria-a-day”, as the 21st century equivalent of “an apple a day”, keep the doctor and the weight away?”
A study in which bacteria engineered to secrete anorexigenic lipids were shown to reduce murine obesity. David says, “Given that diet, drug and exercise regimes for obese humans have not proven to be very effective, a microbiome-based approach may be a real alternative.”
“Dr Spock’s vocal gesture “live long and prosper” and suffer no pain would appear to be a recipe for a good life. At least it appears so for mice – and perhaps for humans too.”
Mice lacking capsaicin receptors (TRPV1 pain receptors) not only show impaired nociception but also increased longevity, living 15% longer than control mice, and a more youthful profile.
“You smell like a goat” is not a turn on for human beings but, perhaps not surprisingly, it is for goats.”
A group in Japan have found the magic pheromone molecule that turns on female goats. David comments, “There are fascinating potential implications from this work for human sexual attractiveness.”
“The late Bob Marley once observed that “with good music you feel no pain”. However, many people with or without good music do feel pain and pain constitutes a major public health problem.”
David Triggle on the mechanisms of pain sensitivity. There may be link between epigenetic DNA methylation and differential pain sensitivity. This could lead to potential clues to better clinical control of pain and the possible role of epigenetics in the abuse of pain medications.
Here’s to more great writing and recommended articles in 2015!